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GlyR is a member of the nicotinicoid receptor superfamily that includes the GABA A receptor (GABA A R), the excitatory nicotinic acetylcholine receptors (nAChR) and the serotonin type 3 receptor (5HT 3 )

(PubMed) Clark LC, Combs GF, Jr., Turnbull BW, et al

Since mitochondria are the main source of cell energy supply, the relationship between ferroptosis and metabolic reprogramming may also play a role in other highly metabolic ovarian diseases such as PCOS and ovarian tumors, in addition to ovarian aging

Because ONL belongs to the photoreceptor cell layer, it often experiences a decrease in thickness and a decrease in the number of rod and cone cells when damaged, leading to problems such as decreased visual sensitivity, loss of field of view, and color vision abnormalities (Shang et al., 2014)